Swiss Pharmaceuticals 5-Amino-1MQ 60 caps

What is 5-AMINO-1?

5-amino-1MQ is a small molecule drug that works by blocking the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a significant role in metabolism and energy and is predominantly active in adipose tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as the “longevity gene” for its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.

In simple words

This means that 5-amino-1MQ allows your body to burn fat for energy, while preferably maintaining muscle mass. 5-amino-1MQ is safe and effective for reversing and preventing diet-induced obesity. It is a potentially superior treatment option for individuals with (or at risk for) type 2 diabetes and other metabolic comorbidities of obesity. Additionally, the activation of SIRT1 via increased NAD+ suggests that 5-amino-1MQ is a good option for patients looking to develop a
comprehensive anti-aging protocol.

There is a critical need for new drugs with a mechanism of action that reduce the burden of obesity, osteoarthritis, cardiovascular disease, cancer, Parkinson’s disease, kidney disease, metabolic disorders, and other associated chronic metabolic comorbidities.

Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme with recently identified roles in cellular metabolism and energy homeostasis. Studies indicate that this enzyme slows down the process by which our bodies metabolize fat cells. Most people have trouble losing weight, and when this enzyme is elevated, they have a harder time trying to shed pounds of excess fat. Excess weight leads to an increase in the NNMT enzyme, which leads to slower fat metabolism, which leads to excess weight gain. It’s a vicious cycle. Research suggests that a potent NNMT inhibitor “5-amino-1mq” significantly reduced body weight and white fat mass, reduced adipocyte size, and lowered total plasma cholesterol levels.

These findings support the development of small molecule NNMT inhibitors as therapeutics to reverse diet-induced obesity and validate NNMT as a viable target for the treatment of obesity and related metabolic conditions.

Advantages:

NNMT inhibitors as therapy to reverse diet-induced obesity.
NNMT is a valid target for the treatment of obesity and related metabolic diseases.
Prevent adipogenesis and reverse diet-induced obesity. NNMT expression is upregulated in white adipose tissue (WAT). It has significantly higher activity in WAT compared to its activity in brown adipose tissue, liver, and lung.
NNMT inhibitors had no impact on food intake. However, they did produce significant reductions in body weight, WAT mass, adipocyte size, and cholesterol levels with negligible …(this is where the text ended in the copy provided)…